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Munich - San Diego

German - US-American Collaboration in Computational Neuroscience

"Hippocampal representation of auditory und spatial sequences"

The present proposal is aimed at identifying whether auditory and spatial stimulus sequences are encoded with related mechanisms in the hippocampus of the Mongolian gerbil, which is a hearing-specialist among rodent species. The capability to present auditory stimuli with high temporal precision and in combination with arbitrary visual stimuli in a virtual maze will be used to identify how the learning of sequences that include acoustic features is supported by the hippocampus. The hypothesizes of the project is that the hippocampus uses the same network mechanisms for all sequence encoding, irrespective of stimulus modality. In particular, it is expected to find that the sequential activation of auditory cells in the hippocampus ­ analogously to sequences of place cells ­ shows theta phase precession and time-compressed replay.

 


The following scientists take part in this collaboration:

  • Stefan Leutgeb, Division of Biological Sciences, University of California, San Diego, USA
  • Christian Leibold, Department Biology II, Ludwig Maximilians University, Munich

 

German Coordinator:

Prof. Dr. Christian Leibold
Computational Neuroscience
Department Biology II
Ludwig Maximilians University Munich        
Großhaderner Strasse 2
D-82152 Planegg-Martinsried

Phone: +49 (0) 89 / 2180-74802
Fax: +49 (0) 89 / 2180-74803
e-mail: leibold@bio.lmu.de


 

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