Animal Research and Computational Neuroscience
Through optimization and exchange of methods and data, Computational Neuroscience significantly contributes to limiting animal experiments to a minimum, while achieving a maximum of scientific insight. Computer simulations and theoretical models may even replace some experiments altogether.
Even this young discipline, however, can not do without any experimental data. Animal experiments will continue to be necessary in the future, in order to clarify basic questions about the function of the nervous systems of humans and animals, to acquire basic data for the design of models, to challenge hypotheses and to safely test medical or technological applications before they are applied in humans.
The scientists of the Bernstein Network are firmly committed to the 3R principles ("refine, reduce, and replace"). All research is designed such that animal experiments get refined, the number of experiments and animals used is reduced, and, wherever possible, animal experiments are replaced by alternative metods.
News on the ongoing redefinition of animal welfare legislation in Europe:
- New EU directive on the protection of animals used for scientific purposes (2010/63/EU)
- Position of FENS (Federation of European Neuroscience Societies) on the new directive:
- Position of ESF-EMRC (Standing Committee of the European Science Foundation) on the new directive:
- Joint statement by FENS (Federation of European Neuroscience Societies), JNS (Japanese Neuroscience Society) and SfN (Society for Neuroscience):
- Declaration of Basel:
Website of the "Basel Declaration" initiative
Text of the declaration
- Current version of German animal welfare legislation:
- German Tierschutz-Versuchstierverordnung:
- Nature (Dec 06, 2010):
"Basel declaration defends animal research"
- Nature (Dec 08, 2010):
- Neuron (Sept 20, 2012):
"Implementing the 3Rs in Neuroscience Research: A Reasoned Approach"
Publications about animal research in general:
- FENS-SfN joint statement on the importance of non-human primates in biomedical research
- Basic Neuroscience Research with Nonhuman Primates: A Small but Indispensable Component of Biomedical Research.
Neuron, Volume 82, Issue 6, p1200-1204, 18 June 2014
- Special issue of the Bernstein Newsletter:
- SfN brochure:
"Translational Neuroscience Accomplishments"
- Comprehensive information about brain research on non-human primates:
Website of the Logothetis lab
Max-Planck-Institute for biological Cybernetics, Tübingen (BCCN Tübingen)
- Animal research and welfare:
Website of the German Research Foundation (DFG)
- FENS Committee on Animals in Research (CARE)
- Understanding Animal Research
- Los Angeles Times:
"Why I use animals in my research"
- Sign on San Diego:
"Animal research and medical progress"