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When in Striatum, Avoid Thy Neighbour

Computational models predict the spatial connection profile among nerve cells necessary to model striatal neuronal activity observed in behaving animals.

Striatal network models with monotonically decreasing (top,left) or non-monotonical (bottom,left) connectivity profiles give rise to quite different neuronal activity patterns (right). Blue: no significant patterning, red: activated neuron clusters.

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